NAD+ Protocol — Verum Health

What It Is

Mechanism of Action

NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme present in every living cell. It functions as an electron carrier in redox reactions, a substrate for enzymes regulating cellular aging, and a signaling molecule in metabolic pathways. NAD+ levels decline with age, stress, and metabolic dysfunction.

NAD+ repletion through physician-supervised protocols has been studied for its role in restoring cellular energy metabolism, activating longevity pathways, and supporting genome stability. Individual outcomes may differ. This protocol is not intended to diagnose, treat, cure, or prevent any disease.

Mechanism	Biological Effect
Electron carrier (NAD⁺↔NADH)	ATP production, redox balance
Sirtuin substrate	Gene regulation, mitochondrial biogenesis, longevity
PARP substrate	DNA repair, genome stability
cADPR/NAADP formation	Calcium signaling, metabolism control
NAD⁺/NADH ratio	Energy-sensing and metabolic regulation
Anti-aging support	Enhanced mitochondrial function, reduced senescence

Who It's For

Candidate Profile

Your physician will determine eligibility based on your complete health intake. The following profiles are commonly associated with NAD+ candidates:

Cellular Energy Decline

Individuals with fatigue, cognitive decline, or mitochondrial concerns seeking NAD+ repletion.

Longevity Protocol

Those with established longevity protocols incorporating NAD+ as a foundational cellular support layer.

Metabolic Optimization

Individuals pursuing metabolic efficiency, insulin sensitivity, and mitochondrial biogenesis support.

DNA Repair Support

Individuals seeking physician-reviewed genome stability and anti-senescence support.

Timeline

What the Clinical Literature Indicates

All outcome language below reflects what has been observed in clinical and preclinical settings. Individual outcomes may differ significantly. These are not guarantees.

Weeks 1–2

Acute NAD+ repletion. Energy and mental clarity improvements may occur early. Individual outcomes vary.

Weeks 2–8

Progressive mitochondrial and metabolic benefits may emerge with sustained administration. Results vary significantly.

Ongoing

Long-term NAD+ support reviewed periodically by your physician. Protocol adjusted based on clinical response.

What's Included

Your Protocol Package

Physician consultation — Virtual intake review and protocol consultation with your assigned NP/MD

Valid prescription — Issued by your attending physician upon protocol approval

Pharmacy-dispensed compound — From our licensed 503A compounding pharmacy partner

Follow-up check-in — Physician review at protocol midpoint; reorder pathway established

Safety

Clinical Considerations

Your physician will review your complete health history before determining eligibility.

Active malignancy: NAD+ supports cell survival pathways. Reviewed carefully in oncology contexts.

Current medications: Disclose all medications. Interactions reviewed at intake.

Niacin sensitivity: Some NAD+ precursors may cause flushing. Physician will determine appropriate form.

FAQ

Common Questions

Is NAD+ FDA-approved? +

This compound is not FDA-approved as a drug. It is dispensed as a compounded medication through licensed 503A compounding pharmacies operating under FDA guidelines. All Verum Health protocols require a valid physician prescription.

What does the consultation involve? +

After completing your HIPAA-secure health intake, a physician or NP will review your medical history, current medications, goals, and contraindications. If you're a candidate, a virtual consultation is scheduled — typically 15–20 minutes. Turnaround is 24–48 hours from intake submission.

Can I combine this with other protocols? +

Protocol stacking is reviewed on a case-by-case basis during your physician consultation. Any combination protocol is evaluated for safety and clinical appropriateness.

How do I reorder? +

Reorders are managed through your patient portal. A follow-up physician check-in is required at protocol completion before continuation is authorized.