Education

AOD-9604

What it is

AOD-9604 is a modified fragment of the C-terminal region of human growth hormone. It was developed to study fat metabolism separately from the other actions of full-length growth hormone.

What the research says

  • In obese mice, chronic treatment with a growth hormone C-terminal fragment was reported to change fat metabolism [1].
  • A related mouse study examined effects on lipid metabolism, including in animals lacking the beta-3 adrenergic receptor [2].
  • We did not find peer-reviewed human trial results for AOD-9604 in the sources we reviewed.

Regulatory status

AOD-9604 is research-stage. It is not FDA approved for any use, and compounded versions are not FDA approved. Where prescribed, compounded versions are prepared by state-licensed 503A compounding pharmacies.

Safety and side effects

We did not find peer-reviewed human safety data for AOD-9604. Animal studies cannot show what side effects occur in people. A licensed healthcare provider should review your history, medications and goals.

Is it right for you?

Only a licensed healthcare provider can decide whether any treatment is appropriate for you.

Frequently asked questions

What do studies say about AOD-9604?

Animal studies reported changes in fat metabolism [1][2]. We did not find peer-reviewed human trial results.

Is AOD-9604 approved by FDA?

No. AOD-9604 is not FDA approved and is research-stage. Compounded versions are not FDA approved.

Do I need a prescription for AOD-9604?

Yes. Prescription only, requires evaluation by a licensed provider. A provider decides whether it is appropriate for you.

Sources

  1. Heffernan MA, et al. Int J Obes Relat Metab Disord, 2001 (mouse study; PubMed 11673763). https://pubmed.ncbi.nlm.nih.gov/11673763/
  2. Heffernan M, et al. Endocrinology, 2001 (mouse study; PubMed 11713213). https://pubmed.ncbi.nlm.nih.gov/11713213/

AOD-9604 content on this page is for education. Compounded medications are not FDA approved. Prescription only, requires evaluation by a licensed provider. Educational content only, not medical advice.

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