Semax and Selank are neuropeptides studied for cognitive enhancement, neuroprotection, anxiety reduction, and neurotrophic factor upregulation. Physician-reviewed. Prescription required.
Semax is a synthetic analogue of the ACTH fragment 4-10 developed in Russia. It acts through modulation of neurotrophic, neurotransmitter, and neuroprotective pathways in the central nervous system. Selank is a synthetic peptide developed from a fragment of Interleukin-1 receptor antagonist, best known for its anxiolytic, nootropic, and immunomodulatory properties — acting through a variety of neurochemical, immunological, and regulatory mechanisms.
Used together or individually, Semax and Selank target complementary aspects of cognitive and neurological function — Semax through BDNF/NGF upregulation and Selank through GABAergic modulation and HPA axis regulation. Individual outcomes may differ. This protocol is not intended to diagnose, treat, cure, or prevent any disease.
| Mechanism | Biological Effect |
|---|---|
| Neurotrophin upregulation (BDNF/NGF) | Neuron survival, plasticity |
| Neurotransmitter modulation | Cognitive enhancement, mood balance |
| Neuroprotection & antioxidant activity | Protection from ischemia |
| Anti-inflammatory CNS effects | Reduced neuroinflammation |
| HPA axis modulation | Stress resilience |
| Mechanism | Biological Effect |
|---|---|
| GABAergic modulation | Anxiolytic effects |
| Monoamine neurotransmitter regulation | Mood balance, cognitive support |
| Immunomodulation | Reduced inflammation, stress resilience |
| HPA axis control | Lower cortisol, improved stress response |
| Cognitive enhancement | Memory, attention, executive function |
Your physician will determine eligibility based on your complete health intake. The following profiles are commonly associated with Semax / Selank protocol candidates in clinical practice:
Cognitive Enhancement
Individuals seeking physician-supervised cognitive function support through neurotrophin upregulation.
Anxiety & Stress
Individuals with anxiety or HPA dysregulation where Selank's GABAergic effects may be clinically relevant.
Neuroprotection
Individuals pursuing physician-reviewed neurological protection and BDNF support.
Executive Performance
High-output executives seeking physician-supervised cognitive optimization protocols.
Determine your candidacy
A physician will review your intake and make eligibility determination within 24–48 hours.
All outcome language below reflects what has been observed in clinical and preclinical settings. Individual outcomes may differ significantly. These are not guarantees.
Dosing is determined individually by your assigned physician. The following represents typical ranges discussed in clinical literature. Do not self-administer or adjust dosing without physician guidance.
Typical Range
Semax: 300–900 mcg/day; Selank: 250–500 mcg/day
Administration
Nasal spray or subcutaneous (physician-determined)
Duration
4–12 weeks (physician-determined)
Frequency
Once to twice daily (physician-determined)
These ranges are indicative only. Your physician will prescribe the specific dose and schedule appropriate for your clinical profile.
Physician consultation — Virtual intake review and protocol consultation with your assigned NP/MD
Valid prescription — Issued by your attending physician upon protocol approval
Pharmacy-dispensed compound — Dispensed by our licensed 503A compounding pharmacy partner
Follow-up check-in — Physician review at protocol midpoint; reorder pathway established
Your physician will review your complete health history before determining eligibility. The following are commonly reviewed clinical considerations.
Begin your Semax / Selank protocol.
Complete your intake. Physician review within 24–48 hours.
Physician-reviewed. Pharmacy-dispensed. Prescription required before any order is fulfilled.
Prescription required. Results may vary. Individual outcomes may differ.
Semax and Selank are Russian-developed nootropic peptides. Semax enhances focus, motivation, and cognitive performance. Selank reduces anxiety and stress while improving mental clarity. They are often used together for balanced cognitive enhancement.
Both are available as nasal sprays at Verum Health, providing rapid CNS delivery. The intranasal route efficiently crosses the blood-brain barrier.
Both have been used in Russia for decades as prescription medications with a well-established safety profile. They are well-tolerated with minimal side effects reported in clinical experience.
Yes. Semax is stimulating (enhances drive, focus, BDNF). Selank is calming (reduces anxiety, improves mood stability). Many patients use both — Semax in the morning, Selank as needed for stress or anxiety relief.