NAD+ is a critical coenzyme studied for mitochondrial function, DNA repair, sirtuin activation, and cellular energy metabolism. Physician-reviewed. Prescription required.
NAD+ is a critical coenzyme in cellular metabolism that functions as an electron carrier, substrate for enzymes, and regulator of cellular energy and signaling pathways. It participates in multiple biochemical and signaling processes essential for metabolism, DNA repair, and aging.
NAD+ repletion through physician-supervised protocols has been studied for its role in restoring cellular energy metabolism, activating longevity pathways, and supporting genome stability. Individual outcomes may differ. This protocol is not intended to diagnose, treat, cure, or prevent any disease.
| Mechanism | Biological Effect |
|---|---|
| Electron carrier (NAD⁺↔NADH) | ATP production, redox balance |
| Sirtuin substrate | Gene regulation, mitochondrial biogenesis, longevity |
| PARP substrate | DNA repair, genome stability |
| cADPR/NAADP formation | Calcium signaling, metabolism control |
| NAD⁺/NADH ratio | Energy-sensing and metabolic regulation |
| Anti-aging support | Enhanced mitochondrial function, reduced senescence |
Your physician will determine eligibility based on your complete health intake. The following profiles are commonly associated with NAD+ protocol candidates in clinical practice:
Cellular Energy Decline
Individuals with fatigue, cognitive decline, or mitochondrial concerns seeking physician-supervised NAD+ repletion.
Longevity Protocol
Individuals with established longevity protocols incorporating NAD+ as a foundational cellular support layer.
Metabolic Optimization
Individuals pursuing metabolic efficiency, insulin sensitivity, and mitochondrial biogenesis support.
DNA Repair Support
Individuals seeking physician-reviewed genome stability and anti-senescence support.
Determine your candidacy
A physician will review your intake and make eligibility determination within 24–48 hours.
All outcome language below reflects what has been observed in clinical and preclinical settings. Individual outcomes may differ significantly. These are not guarantees.
Dosing is determined individually by your assigned physician. The following represents typical ranges discussed in clinical literature. Do not self-administer or adjust dosing without physician guidance.
Typical Range
100–500 mg/day (route-dependent)
Administration
IV, subcutaneous, or nasal spray (physician-determined)
Duration
Ongoing with periodic reassessment
Frequency
Daily to weekly IV (physician-determined)
These ranges are indicative only. Your physician will prescribe the specific dose and schedule appropriate for your clinical profile.
Physician consultation — Virtual intake review and protocol consultation with your assigned NP/MD
Valid prescription — Issued by your attending physician upon protocol approval
Pharmacy-dispensed compound — Dispensed by our licensed 503A compounding pharmacy partner
Follow-up check-in — Physician review at protocol midpoint; reorder pathway established
Your physician will review your complete health history before determining eligibility. The following are commonly reviewed clinical considerations.
Begin your NAD+ protocol.
Complete your intake. Physician review within 24–48 hours.
Physician-reviewed. Pharmacy-dispensed. Prescription required before any order is fulfilled.
Prescription required. Results may vary. Individual outcomes may differ.
NAD+ therapy supports energy production, DNA repair, brain function, metabolic health, and cellular aging. Benefits include improved energy, cognitive clarity, faster recovery, and anti-aging effects.
Verum Health offers NAD+ as a subcutaneous injectable (100mg/mL, 5mL) and as a nasal spray (10mg/0.1mL) for cognitive focus. Both are prescription-grade from our licensed 503A pharmacy.
Subcutaneous injection delivers NAD+ with comparable bioavailability to IV therapy at a fraction of the cost, without a 2-4 hour clinic visit. Daily low-dose subQ maintains more consistent NAD+ levels than periodic IV spikes.
Most patients notice improved energy and mental clarity within 1-2 weeks. Deeper cellular benefits develop over 1-3 months of consistent use.